U0126
Supplier:
Catalogue number:
SM107-100
Size:
100 mg
Product is available in:
Vandetanib is an antagonist of VEGFR and EGFR families. Specifically inhibits kinase activity of Flk-1. It is also an inhibitor of Flt-4. Vandetanib is not sensitive to PDGFR beta, Flt1, Tie-2 and FGFR1, while almost has no activity against MEK, CDK2, c-Kit, erbB2, FAK, PDK1, Akt and IGF-1R. Vandetanib has been shown to influence in the osteoblast differentiation process in-vitro.
Product Type:
Peptides & proteins
CAS Number:
443913-73-3
Alternative Names:
Caprelsa, Zactima, ZD6474, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine