Sunitinib
Supplier:
Catalogue number:
SM101-1000
Size:
1 g
Product is available in:
Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFR beta. It also inhibits c-Kit. Sunitinib inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Sunitinib has been shown to impinge on the osteoblast differentiation process in-vitro. It exhibits antiangiogenic and antitumor activity in multiple xenograft models.
Product Type:
Peptides & proteins
CAS Number:
557795-19-4
Alternative Names:
SU-11248, Sutent, PHA-290940AD, PNU-290940AD, N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide