ALK5 Inhibitor II
Supplier:
Catalogue number:
SM09-10
Size:
10 mg
Product is available in:
ALK5 Inhibitor II is a cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50 = 23 nM, 4 nM and 18 nM for binding, auto-phosphorylation and cellular assay in HepG2 cells of TGF-β RI kinase, respectively). TGF-β RI (ALK5) Inhibitor II affects a panel of 9 closely related kinases including p38 MAPK. ALK5 can replace Sox2 for generation of induced pluripotent stem cells (iPSC).
Product Type:
Peptides & proteins
CAS Number:
446859-33-2
Alternative Names:
2-(3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine