PNU 74654
Supplier:
Catalogue number:
10-4519-02
Size:
25 mg
Product is available in:
Wnt pathway blocker / PNU-75654 disrupts the Wnt signaling pathway via inhibition of the interaction (KD50 = 450 nM) between β-catenin and T cell factor 4 (Tcf4).
Product Type:
Biochemicals & reagents
CAS Number:
113906-27-7
Reference:
1) Trosset et al. (2006) Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening Proteins 64 60
Storage Temperature:
-20°C
Additional Information:
TARGET: Transcription factor -- PATHWAY: Wnt; Transcription -- DISEASE AREA: Cancer