Rbin-1
Supplier:
Catalogue number:
10-4606-02
Size:
25 mg
Product is available in:
Eukaryotic ribosome assembly inhibitor / Rbin-1 is potent (GI50 = 136 nM) and reversible inhibitor of eukaryotic ribosome assembly. The biochemical target of Rbin-1 is Midasin (Mdn1), an essential AAA+ protein. Blocking of Mdn1 by Rbin-1 inhibits the processing of pre-60S particles, important pre-ribosomal subunits produced in the nucleolus.
Product Type:
Biochemicals & reagents
CAS Number:
328023-11-6
Reference:
1) Kawashime et al. (2016), Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis; Cell 167 512
Storage Temperature:
-20°C
Additional Information:
TARGET: Ribosome -- PATHWAY: Protein synthesis