BMS-202
Supplier:
Catalogue number:
10-4900-01
Size:
5 mg
Product is available in:
PD-1/PD-L1 inhibitor / BMS-202 (1675203-84-5) inhibits (IC50 = 18nM) formation of the PD-1/PD-L1 complex via binding to PD-L1 and inducing dimerization.1,2
Product Type:
Biochemicals & reagents
CAS Number:
1675203-84-5
Alternative Names:
PD-1/PD-L1 Inhibitor 2
Reference:
1) Zak et al. (2016), Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1); Oncotarget 7 30323 2) Guzik et al. (2017), Small-molecule inhibitors of the programmed cell death -1/programmed cell death -ligand 1(PD-1/PD-L1) interaction via transiently induced protein states and dimerization of PD-L1; J. Med. Chem. 60 5857
Storage Temperature:
-20°C
Additional Information:
TARGET: PD-1 -- PATHWAY: Apoptosis inducer -- RESEARCH AREA: Immunology; Cell death -- DISEASE AREA: Cancer