Propidium Iodide
Fluorescent stain for dead/dying cells / Red fluorescent DNA stain.1,2 Membrane impermeable to live cells but permeable to dead or damaged cells and thus may be used for identifying cell viability or as a counterstain.3,4 Binds to DNA by intercalation and is suitable for fluorescence microscopy and flow cytometry.2 Ex.: 488-535 nm and Em.: 617 nm.
Biochemicals & reagents
25535-16-4
1 Coder et al. (1997), Assessment of cell viability; Curr. Protoc. Cytom., Suppl. 15 2 Edwards et al. (2007), High-throughput cytotoxicity screening by propidium iodide staining; Curr. Protoc. Cytom., Unit 9.24 3 Sawai and Domae (2011), Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells; Biochem. Biophys. Res. Commun., 411 569 4 Pizato et al. (2018), Omega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative breast cancer cells; Sci. Rep., 8 1952
-20°C
TARGET: Substrate / Probe; DNA -- RESEARCH AREA: Cell death