9-Hydroxyrisperidone
Risperidone metabolite / Pharmacologically active metabolite of risperidone, an atypical antipsychotic agent.1 Displays high affinity for serotonin 5-HT2A receptors as well as dopamine D2 receptors.2,3
Biochemicals & reagents
144598-75-4
Paliperidone
1) Beijsterveldt et al. (1994), Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat; Psychopharmacology, 114 53 2) Leysen et al. (1994), Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity; J. Clin. Psychiatry, 55 suppl: 5 3) Schotte et al. (1996), Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding; Psychopharmacology (Berl.), 124 57
RT
TARGET: Monoamine receptor; Serotonin; Dopamine -- RESEARCH AREA: Neuroscience -- DISEASE AREA: Heart disease; Mood disorders