Mayflower Biosciences offers an extensive collection of biochemicals that act on various enzymes for both research and drug discovery programs. For bulk qualities, contact us at sales@mayflowerbio.com for a no-obligation quote.
Compound (primary activity*)
* listed compounds act on listed targets, even though the primary activity may highlight a different target class. See the individual product page for more detail or contact us at sales@mayflowerbio.com for product documentation.
Acetylcholinesterase/Butyrylcholinesterase
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ABT-418 HCl (Nicotinic acetylcholine receptor agonist; cognition enhancer) Galanthamine HBr (Acetylcholinesterase inhibitor) Huperzine A (Acetylcholinesterase inhibitor) |
PNU 282987 (nAChR agonist) Varenicline tartrate (α4ß2 partial agonist / Smoking cessation aid) |
Acetyltransferase
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Anacardic acid (HAT inhibitor) Arecoline HBr (ACAT1 inhibitor) C-646 (HAT inhibitor) CPTH2 (HAT inhibitor) CTPB (p300 HAT activator) Embelin (XIAP inhibitor, Apoptosis inducer) |
Garcinol (HAT inhibitor) Phenylhexyl isothiocyanate (Chemopreventive; HDAC inhibitor; p53 reactivator) Remodelin (Acetyl-transferase NAT10 inhibitor) TTK21 (CBP/p300 histone acetyltransferase activator) WM-1119 (KAT6A HAT inhibitor) |
Acyltransferase
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(R)-(+)Etomoxir Na (Carnitine palmitoyltransferase inhibitor) IWP-2 (Porcn inhibitor: Wnt/b-catenin pathway inhibitor) |
IWP-4 (Porcn inhibitor: Wnt/Beta-catenin pathway inhibitor) Wnt-C59 (Porcupine inhibitor) |
Adenylyl cyclase
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Forskolin (Adenylate cyclase activator) NKY-80 (Adenylate cyclase inhibitor) |
ST-034307 (Adenylate cyclase 1 inhibitor, analgesic activity) |
ATP synthase
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Oligomycin A (Mitochondrial ATPase inhibitor) |
Oligomycin complex (Mitochondrial ATPase inhibitor) |
ATPase
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Apoptolidin (Apoptosis inducer) Bafilomycin A1 (Vacuolar H+ ATPase inhibitor) BRM014 (BRM / BRG1 ATPase inhibitor) CDN1163 (SERCA activator) Concanamycin A (V-ATPase inhibitor) DBeQ (p97 inhibitor) MDBN (p97 inhibitor) Metformin HCl (Anti-diabetic agent) |
ML241 (p97 AAA ATPase inhibitor) Mycalolide B (Actin depolymerizing agent) Omeprazole (Proton Pump inhibitor, Antiviral Activity) Ouabain (Na+ K+ ATPase inhibitor) S-Farnesyl-L-cysteine methyl ester (Prenylated amino acid) Thapsigargin (SERCA inhibitor) Xanthohumol (VCP inhibitor / Autophagy inhibitor) |
COX (Cyclooxygenase)
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Celecoxib (COX II inhibitor) Curcumin (Antiinflammatory) Oxaprozin (NFκB inhibitor) |
Rofecoxib (Selective COX-2 inhibitor) SC-560 (Selective COX-1 inhibitor) |
Dehydrogenase
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A77 1726 (DHODH inhibitor) AGI-5198 (R132 mutant isocitrate dehydrogenase inhibitor) Brequinar sodium (Dihysroorotate dehydrogenase inhibitor, antiviral) CBR-5884 (PHGDH / serine biosynthesis inhibitor) CPI-613 (KGDH and PDH inhibitor) Dyclonine HCl (Mitochondrial function enhancer) Enasidenib (IDH2 inhibitor) Eniluracil (Dihydropyrimidine dehydrogenase inhibitor) Gimeracil (Dihydropyrimidine dehydrogenase inhibitor) iGP-1 (Mitochondrial GPDH inhibitor) |
Koningic acid (Glyceraldehyde-3-phosphate dehydrogenase inhibitor) Leflunomide (Immunosuppressant) Mycophenolate mofetil (Immunosuppressant prodrug) Mycophenolic acid (Immunosuppressant) NHI-2 (LDHA inhibitor) R162 (Glutamate Dehydrogenase 1 inhibitor) Ribavirin (Antiviral guanosine ribonucleoside analog) Visnagin (Protects against doxorubicin-induced cardiomyopathy) Vorasidenib (Isocitrate dehydrogenase (IDH) 1/2 inhibitor) |
DUB
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b-AP15 (NSC-687852) (DUB inhibitor) IU1 (USP14 inhibitor) LDN-57444 (DUB inhibitor) ML323 (USP1 - UAF1 inhibitor) NSC632839 (DUB inhibitor) P22077 (USP7 inhibitor) |
P5091 (DUB USP7 inhibitor) PR-619 (DUB inhibitor) TCID (DUB inhibitor) Thiolutin (DUB PSMD14 inhibitor) WP-1130 (DUB inhibitor ) |
Galactosidase
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4-MUG (β-Galactosidase fluorogenic substrate) IPTG (animal free) (Induces β-galactosidase in bacteria) |
Migalastat (Galactosidase inhibitor; pharmacological chaperone) |
Glutaminase
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BPTES (Glutaminase GLS1 inhibitor) CB-839 (Glutaminase inhibitor) |
GAC Inhibitor 968 (Glutaminase C inhibitor) |
Lipase
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ABX-1431 (MAGL inhibitor) Atglistatin (ATGL inhibitor) JZL-184 (MAG lipase inhibitor) |
Orlistat (DAG Lipase-α inhibitor) RHC-80267 (U-57908) (DAG Lipase inhibitor) |
LOX (Lipoxygenase)
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Baicalein (Inhibitor of protein tyrosine kinase in leukemia (CEM cells)) EPA free acid (omega-3 fatty acid) |
Zileuton (5-LO inhibitor) |
Methyltransferase
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Entacapone (COMT inhibitor - anti-Parkinsons) N-Acetyl-S-farnesyl-L-cysteine (S-Farnesylcystine methyl transferase inhibitor) |
Sinefungin (Methyltransferase inhibitor) Tolcapone (COMT inhibitor; TTR aggregation inhibitor) |
Monoamine oxidase
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Deprenyl (MAO-B inhibitor) Harmine HCl (MAO-A and DYRK inhibitor) Hypericin (Protein kinase C inhibitor) |
Rasagiline mesylate (MAO-B inhibitor, Neuroprotective) Safinamide (MAO-B inhibitor, Parkinson's therapeutic) |
NOS (Nitric oxide synthase)
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1400W (iNOS inhibitor) Diphenylene iodonium chloride (Flavoprotein inhibitor) |
TRIM (Nitric oxide synthase inhibitor) |
Nox (NADH/NADPH oxidase)
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GKT-137831 (NADPH oxidase NOX1/4 inhibitor) Gliotoxin (Immunomodulator) HQNO (NADH oxidase inhibitor) |
Leonurine (Neuroinflammation inhibitor) VAS-2870 (Nox inhibitor) |
PARP
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3-Aminobenzamide (PARP inhibitor) Iniparib (PARP inhibitor) ME-0328 (PARP3 inhibitor) Minocycline HCl (Neuroprotective; antiapoptotic) Olaparib (PARP1 inhibitor) |
PJ-34 HCl (PARP1,2 inhibitor) Rucaparib phosphate (PARP1 inhibitor) UPF-1069 (PARP-2 inhibitor) Veliparib 2HCl (PARP 1&2 inhibitor) |
PDE (Phosphodiesterase)
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Anagrelide HCl (PDE2 inhibitor) BC-11-38 (PDE11 inhibitor) BML-288 (PDE2 inhibitor) BRL-50481 (PDE7 inhibitor) Cilostamide (PDE3 inhibitor) Cilostazol (PDE3A inhibitor) Dipyridamole (PDE5 inhibitor) EHNA HCl (PDE2 inhibitor) IBMX (PDE inhibitor (pan-spec)) Ibudilast (Neuroinflammation inhibitor (PDE pan-inhibitor)) |
Lisofylline (Anti-diabetic and Antiinflammatory agent) Ro 13-6438 (Quazinone) (PDE3 inhibitor) RO 20-1724 (PDE4 inhibitor) Roflumilast (PDE4 inhibitor) Rolipram (PDE4 inhibitor) Sildenafil citrate (PDE5 inhibitor) Sulindac Sulfide (NFκB inhibitor) Sulindac Sulfone (Modulates β-catenin-mediated effects) Vinpocetine (PDE1 inhibitor) |
Phospholipase
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m-3M3FBS (Phospholipase C activator) NOBA (Phospholipase substrate) NSC47924 (PHLP phosphatase inhibitor / Laminin inhibitor) ONO-RS-082 (Phospholipase A2 inhibitor) |
Phosphatidylethanol (PLD assay standard) Surfactin (Lipopeptide biosurfactant) U-73122 (PLC inhibitor) U-73343 (U-73122 negative control) |
PPIase
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Ascomycin (FKBP ligand; immunosuppressant) Cycloheximide-N-ethylethanoate (FKBP12 inhibitor) |
FK-506 (FKBP inhibitor) Sulfopin (Potent and selective covalent inhibitor of peptidyl-prolyl isomerase NIMA interacting-1 (Pin1)) |
Prolyl hydroxylase
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1,4-DPCA (Prolyl hydroxylase inhibitor) DMOG (Inhibits prolyl hydroxylase domain-containing proteins) |
Roxadustat (Prolyl hydroxylase domain inhibitor / HIF stabilizer) |
Protein deacetylase
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AK-7 (SIRT2 inhibitor) Apicidin (HDAC inhibitor) BG45 (HDAC3 selective inhibitor) BML-210 (HDAC inhibitor) BML-278 (SIRT1 activator) BRD73954 (Selective HDAC6/8 inhibitor) CI-994 (HDAC inhibitor) Dihydroresveratrol (Resveratrol metabolite) EX-527 (SIRT1 inhibitor) Honokiol (SIRT3 activator) HPA (Hexyl-4-pentynoic acid) (HDAC inhibitor) LMK235 (Potent, selective inhibitor of HDAC4/5) MDL-800 (SIRT6 activator) Mocetinostat (Class I HDAC inhibitor) MS-275 (HDAC inhibitor) Na Valproate (HDAC inhibitor) Nicotinamide (SIRT1 inhibitor/essential nutrient) OSS-128167 (SIRT6 inhibitor) Panobinostat (HDAC inhibitor) |
PCI-34051 (HDAC8 inhibitor) Phenylbutyrate Na (HDAC inhibitor) Piceatannol (SIRT1 activator) Resveratrol (Antioxidant/SIRT1 activator) RGFP966 (HDAC3 inhibitor) Romidepsin (HDAC inhibitor) SAHA (Vorinostat) (HDAC inhibitor) Salermide (SIRT 1&2 inhibitor) Santacruzamate A (HDAC2 inhibitor) Scriptaid (HDAC inhibitor) SirtAct (Sirt1 activator) Sirtinol (SIRT inhibitor) Splitomicin (Sirt1 inhibitor) SRT1720 HCl (SIRT1 activator) Tenovin-1 (SIRT1 and 2 inhibitor) TM-2-51 (HDAC8 activator) Triacetyl resveratrol (SIRT activator, prodrug) Trichostatin A (HDAC inhibitor) Tubastatin A · HCl (HDAC-6 inhibitor) |
Protein demethylase
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(±) Tranylcypromine hemisulfate (Demethylase inhibitor) AS-8351 (KDM5B histone demethylase inhibitor) CPI-455 (Lysine demethylase KDM5 inhibitor) Daminozide (KDM2/7 demethylase inhibitor) GSK2879552 (LSD1 inhibitor) GSK-J1 (JMJ H3K27 Demethylase inhibitor (Non-cell permeable)) GSK-J4 (JMJ H3K27 Demethylase inhibitor (Cell Permeable)) |
iJMJD6 (Arginine demethylase JMJD6 inhibitor) IOX 1 (JMJD demethylase inhibitor) JIB-04 (pan-JUMONJI histone demethylase inhibitor) ML324 (JMJD2 inhibitor) PBIT (JARID1 lysine demethylase inhibitor) SP2509 (LSD1 inhibitor) |
Protein methyltransferase
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(R)-PFI-2 HCl (Methyltransferase SETD7 inhibitor) A-196 (SUV420H1/H2 lysine methyltransferase inhibitor) BIX-01294 (Histone Methyl transferase inhibitor+D257) Chaetocin (Lys methyltransferase inhibitor) DZNep (Methyl transferase inhibitor) EED-226 (PRC2 methyltransferase inhibitor) EPZ015666 (PRMT5 inhibitor) GSK126 (EZH2 methyltransferase inhibitor) GSK3326595 (PRMT5 inhibitor) |
SGC707 (PRMT3 inhibitor) Tazemetostat (EZH2 inhibitor) TC-E 5003 (Arginine methyl transferase 1 (PRMT1) inhibitor) UNC0224 (G9a histone methyl transferase inhibitor) UNC0379 (SETD8 inhibitor) UNC1999 (Methyltransferase inhibitor) UNC6934 (NSD2 inhibitor) UNC7145 (UNC6934 Negative control) |
Serine hydrolase
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JNJ-1661010 (FAAH inhibitor) LY2183240 (Anandamide uptake inhibitor) Nonylbenzeneboronic acid (FAAH inhibitor) |
PF-622 (FAAH inhibitor) URB-597 (FAAH inhibitor) |
Telomerase
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BIBR1532 (Telomerase inhibitor) Cycloastragenol (Telomerase activator / Senolytic agent) |
Helenalin (NFκB inhibitor) Mitoquinone mesylate (Mitochondria-targeted antioxidant) |
Topoisomerase
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Camptothecin (Topoisomerase I inhibitor) Daunorubicin HCl (DNA damaging agent - Anticancer agent) Epirubicin HCl (DNA damaging agent) Etoposide (Topoisomerase II inhibitor) ICRF-193 (Topoisomerase II inhibitor) |
Irinotecan HCl (Topoisomerase I inhibitor) SN-38 (DNA topoisomerase I inhibitor) ß-Lapachone (Topoisomerase I inhibitor) Topotecan HCl (DNA topoisomerase I inhibitor) |
Ubiquitin ligase
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CC-90009 (Cereblon modulator/Molecular glue) CFM-4 (CARP-1 mimetic) Heclin (HECT domain containing E3 ubiquitin ligase inhibitor) Iberdomide (Cereblon modulator/Molecular glue) Lenalidomide (Immunomodulator) ML792 (SUMO-activating enzyme (SAE) inhibitor) |
Pomalidomide (Cereblon ubiquitination inhibitor) PRT4165 (E3 ubiquitin ligase inhibitor) SMER3 (E3 UB ligase inhibitor) TAME (Ub-ligase inhibitor) Thalidomide (E3 UB ligase inhibitor) |