Mayflower Biosciences offers an extensive collection of biochemicals that act on ion channels for both research and drug discovery programs. For bulk quantities, contact us at sales@mayflowerbio.com for a no-obligation quote.
Compound (primary activity*)
* listed compounds act on ion channels, even though the primary activity may highlight a different target class. See the individual product page for more detail or contact us at sales@mayflowerbio.com for product documentation.
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1-EBIO (K+ channel activator; Cardiomyocyte differentiation) 2-APB (TRP blocker) 2GBI (Hv1 channel blocker) 4,9-Anhydro-tetrodotoxin (Selective sodium channel blocker) A1899 (Potent and selective K2P3.1 blocker) A-438079 HCl (P2X7 antagonist) A-803467 (NaV1.8 blocker) A-967079 (TRPA1 blocker) AA43279 (Nav 1.1 activator) AC1903 (TRPC5 blocker) Ambroxol HCl (Free radical scavenger) Amiodarone HCl (Pan-specific ion channel blocker) Amlodipine (L-type Ca channel blocker) AP-18 (TRPA1 blocker) Aprepitant (NK-1 antagonist) Arvanil (TRPV1 channel activator) Astemizole (Herg channel blocker) BAY K8644 (L-type calcium channel activator) BCTC (TRPV1 blocker) Bepridil (Calcium channel blocker/active against SARS-CoV2) Capsaicin (natural) (TRPV1 agonist) CBA (TRPM4 blocker) CGP-37157 (MPTP inhibitor) Cromakalim (ATP-sensitive potassium channel opener) Cyclothiazide (AMPA receptor positive allosteric modulator) D(+)-Cycloserine (NMDA, glycine site partial agonist) DEA NONOate (NO donor) Deltamethrin (Calcineurin inhibitor; displays neurotrophic activity) DETA NONOate (NO Donor) Diazoxide (K-ATP channel activator) Diltiazem (Calcium channel blocker) Disopyramide (Sodium channel blocker) Dofetilide (Herg channel blocker) Domoic acid (Marine natural product neurotoxin) E-4031 (Herg channel blocker) Erastin (Ferroptosis inducer) Evodiamine (TRPV1 agonist, antiinflamatory, antiangiogenic) Felodipine (L-type Ca channel blocker) Flecainide acetate (Sodium channel blocker) Flupirtine maleate (K+ channel activator) Gabapentin (Neuropathic pain drug) GFB-8438 (Selective TRPC5 inhibitor) Glyburide (K-ATP channel blocker) GSK-1016790A (TRPV4 channel blocker) GSK-1702934A (TRPC3/6 activator) GSK-417651A (TRPC3/6 blocker) GYY4137 (Hydrogen sulfide donor) HC-030031 (TRPA1 blocker) HC-067047 (TRPV4 blocker) Huperzine A (Acetylcholinesterase inhibitor) Ibotenic acid (NMDA and m GluR agonist) ICA-110381 (Kv7.2/7.3 activator) ICA-121431 (Nav1.1/1.3 inhibitor (selective))
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Icilin (TRPM8 inhibitor) Isopimaric acid (Potassium channel activator) Isradipine (L-type Ca channel blocker) Ivabradine HCl (Heart failure / unstable angina treatment) Kainic acid (Kainate receptor agonist; neurotoxin) KB-R7943 mesylate (TRPC channel blocker) Linopirdine dihydrochloride (Kv7 blocker) Lomerizine (Calcium channel blocker) Lorcainide HCl (Voltage-gated sodium channel blocker) Manidipine dihydrochloride (Calcium channel blocker) MDL29,951 (GPR17 activator) Memantine HCl (NMDA antagonist / Anti-Alzheimer's) Metergoline (Serotonin 5HT1,2,7 antagonist) Minoxidil (KATP channel opener) ML133 HCl (Kir2 potassium channel blocker) ML204 (TRPC4 blocker) ML277 (Potent Kv7.1 activator) ML297 (GIRK inhibitor) ML335 (TREK-1,2 activator) ML365 (Potent and selective K2P3.1 blocker) ML418 (Kir7.1/6.2 blocker) ML-SA1 (TRPML activator) N-Arachidonoyldopamine (Endogenous TRPV1 activator) Nicardipine HCl (L-type Ca channel blocker / MDR inhibitor) Nifedipine (L-type Ca channel blocker) Niguldipine HCl (L-type Ca channel blocker) Nilvadipine (Syk inhibitor and Ca channel blocker) Nimodipine (L-type calcium channel blocker) Nitrendipine (L-type Ca channel blocker) NS 1619 (Selective KCa1.1 activator) Optovin (TRPA1 channel activator) PAPA NONOate (NO Donor) PB28 dihydrochloride (High affinity sigma 2 ligand / Anti-SARS-COV2) Penitrem A (High conductance Ca-activated K channel inhibitor) PF-05089771 (Selective Nav1.7 channel blocker) Pinacidil (Potassium channel opener) Piperine (Up-regulates skeletal muscle metabolism) Polygodial (TRPA1 agonist) Pyr3 (TRPC3 Channel blocker) Ranolazine (Selective sodium channel blocker) Repaglinide (Kir6 blocker) Riluzole (Sodium channel blocker / Neuroprotective) Rufinamide (Anticonvulsant / Improves cognition) SB-366791 (TRPV1 blocker) SB-705498 (TRPV1 antagonist) SKA-31 (Potassium channel activator) SKF525A ∙ HCl (Cytochrome P450 inhibitor) SKF-96365 (TRPC channel blocker) Spermine NONOate (NO Donor) TTA-P2 (T-type calcium channel blocker) Verapamil HCl (L-type Ca channel blocker) Veratridine (Na channel opener) VU0134992 (Kir4.1 blocker) YM-58483 (CRAC channel blocker) |