Mayflower Biosciences offers an extensive collection of biochemicals that act on GPCRs for both research and drug discovery programs. For bulk quantities, contact us at sales@mayflowerbio.com for a no-obligation quote.
Compound (primary activity*)
* listed compounds act on GPCRs, even though the primary activity may highlight a different target class. See the individual product page for more detail or contact us at sales@mayflowerbio.com for product documentation.
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20(S)-Hydroxycholesterol (Smoothened activator) 6,7-ADTN HBr (Dopamine D1 agonist) AdipoRon (Adiponection agonist) AH-6809 (Prostanoid EP antagonist) AH-7614 (GPR120 antagonist) AM251 (Cannabinoid CB1 antagonist) AM-404 (Anandamide transport inhibitor) Amlexanox (TBK1 inhibitor / Antidiabetic) Anandamide (Endogenous cannabinoid) Apomorphine HCl (Dopamine agonist) Aprepitant (NK-1 antagonist) Arecoline HBr (ACAT1 inhibitor) Aripiprazole (Dopamine receptor partial agonist) Arvanil (TRPV1 channel activator) Astemizole (Herg channel blocker) AZD-2098 (CCR4 antagonist) Benzotript (Cholecystokinin antagonist) Benztropine mesylate (Induces remyelination of neurons) Bromocriptine mesylate (Dopamine D2/D3 agonist) Candesartan (Angiotensin II antagonist) Cinacalcet HCl (Calcium sensing receptor (CaSR) agonist) CL-316243 (β3-adrenergic agonist / antiobesity) Clemastine fumarate (Histamine H1 receptor antagonist) Clozapine (base) (Dopamine D2/D4 antagonist) Clozapine N-oxide (DREADD agonist) CLP-3094 (GPR142 antagonist) CPI-444 (Adenosine A2A receptor antagonist) CUR 61414 (Hedgehog pathway antagonist) Cyclopamine (Hedgehog signaling inhibitor) CYM5541 (Allosteric sphingosine-1-phosphate Receptor 3 agonist) DC260126 (GPR40 antagonist) DJ-V 159 (GPRC6A agonist; Stimulates insulin secretion in beta cells) Efaroxan HCl (α2 adrenergic antagonist) EPPTB (TAAR1 antagonist) Fludarabine (DNA synthesis inhibitor) Formoterol hemifumarate (β2 adrenergic agonist) Forskolin (Adenylate cyclase activator) FTY720 HCl (Sphingosine-1-phosphate receptor agonist) Genistein (Tyrosine kinase inhibitor) Ginkgolide B (PAF antagonist) Grapiprant (EP4 receptor antagonist.) GRI-977143 (LPA2 antagonist) GSK-137647 (GPR120 agonist) GSK2636771 (Selective PI3Kß inhibitor) Gue1654 (OXE-R biased antagonist) GW1100 (GPR40 antagonist) GW-9508 (GPR40 agonist) H2L5186303 (LPA2 antagonist) IBMX (PDE inhibitor (pan-spec)) Ibotenic acid (NMDA and m GluR agonist) IPBT-5CA (IBC-293) (GPR109B agonist) Itraconazole (Autophagy inducer / inhibits glioblastoma growth) Jervine (Hedgehog pathway) JNJ-63533054 (GPR139 agonist, supresses morphine intake) JZL-184 (MAG lipase inhibitor) |
L-755,507 (ß3 adrenergic agonist / CRISPR efficiency enhancer) Lomerizine (Calcium channel blocker) Losartan potassium (Angiotensin AT1 antagonist) Lysophosphatidic acid (Oleyl form) (Endogenous LPA receptor agonist) Maraviroc (CCR5 antagonist) MDL29,951 (GPR17 activator) Mirabegron (beta-3 Adrenergic agonist) ML382 (MRGPRX1 positive allosteric modulator) ML401 (EBI2 (GPR183) antagonist) Montelukast sodium (Leukotriene CysLT1 and GPR17 antagonist) MPEP HCl (mGlu5 receptor antagonist) NA-Gly (GPR18 agonist) Nalmefene HCl (Opioid receptor antagonist) Naloxone HCl (Opioid receptor antagonist) NSC23766 (Rac1 GTPase inhibitor) Oleamide (Endogenous sleep inducing ligand) Oleoylethanolamide (GPR119 agonist: stimulates lipolysis) Olodanrigan (Angiotensin II type 2 receptor antagonist) Palmitoylethanolamide (GPR-55 agonist) PD 123319 ditrifluoroacetate (Angiotensin II type II antagonist) PF-4136309 (CCR2 antagonist) Phenoxybenzamine HCl (Calmodulin antagonist) Plerixafor (CXCR4 antagonist) Pranlukast (Leukotriene CysLT1 antagonist and GPR17 antagonist) Preladenant (Adenosine A2A receptor antagonist) Prostaglandin A1 (Endogenous prostaglandin) Prostaglandin E1 (Vasodilator) Prostaglandin E2 (Prostaglandin E (EP) agonist) PSB-1584 (GPR84 agonist) PSB-CB5 (GPR18 antagonist) Purmorphamine (Smoothened activator) Reparixin (CXCR 1/2 allosteric antagonist) Reversine (Reverses differentiated cells to multipotent stem cells) Rimonabant (CB1 antagonist) Rosmarinic acid (Antioxidant) Roxatidine (Histamine H2 antagonist, antiulcer and anti-inflammatory) SAG (Smoothened agonist) SB-225002 (CXCR2 antagonist) SBI-553 (ß-Arrestin-biased NTSR1 modulator) SC-51089 (Prostaglandin E (EP1) antagonist) SCH-202676 (G-protein inhibitor) Sphingosine-1-phosphate (EDG receptor ligand) SR-144528 (Cannabinoid CB2 antagonist) SX-682 (CXCR1/2 inhibitor) Synaptamide (Endogenous agonist at GPR110) Tamoxifen citrate (ER antagonist; GPR30 agonist) Terazocin HCl (Adrenergic antagonist) Terguride (Dopamine D2 agonist) TG 4-155 (EP2 receptor antagonist) Valsartan (Angiotensin antagonist) Vismodegib (Sonic Hedgehog signaling pathway inhibitor) Xanomeline tartrate (Selective M1 Muscarinic agonist) YM-254890 (Gq inhibitor) Zafirlukast (Leukotriene CysLT1 antagonist)
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