BMP-2, human recombinant

Overview

Description

BMP-2 belongs to the bone-growth regulatory factors that are members of the transforming growth factor-beta (TGF-beta) superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. Recombinant Human Bone Morphogenetic protein-2 produced in E. coli is a homodimeric non-glycosylated protein.

Classification

Pathogen: Growth Factors

Target: BMP-2

Alternative Names: BMP-2A

Desc. Detail: Bone Morphogenetic Protein-2

Specifications

Catalog Number: GFH053

Expression System: E.coli

Format: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.

Testing: Alkaline phosphatase activity induced in ATDC-5 cells with an acceptance criteria of 250 ng/mL (ED50), 4 x 10^3 units/mg.

Accession/Uniprot#: P12643

AA#: 230

Sequence:

MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

SPECIES: human

TYPE: lyophilized

Storage & Shipping

Shipping: Cold (4°C)

Storage Temp: at -20°C

Shelf Life: at least 12 months

References & Docs

Supplier: CGS

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SKU GFH053 Categories BMP human, BMP human, Cell Biology, Growth Factors, Growth Factors, Human Growth Factors, Human Growth Factors, Proteins & Peptides, Standard Formulation (BMP human PP), Standard Formulation (BMP human)

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