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Activin A, human recombinant

Overview

Description

Human Activin-A is a 26 kDa disulfide-linked homodimer of two beta A chains, each containing 116 amino acid residues. Activin-A is a TGF-beta family member with a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. The biological activities of Activin-A can be counteracted by inhibins and also by the diffusible TGF-beta antagonist, Follistatin.

Classification

Pathogen: Growth Factors
Target: Activin A
Alternative Names: Inhibin beta-1, FRP, FSH-releasing protein
Desc. Detail: Activin A

Specifications

Catalog Number: GFH006
Expression System: E.coli
Format: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.
Testing: Cytotoxicity of MPC-11 cells with an acceptance criteria of 10 ng/mL (ED50), 1 x 10^5 units/mg.
Accession/Uniprot#: P08476
AA#: 234
Sequence:

MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS

SPECIES: human
TYPE: lyophilized
Shipping: Cold (4°C)
Storage Temp: at -20°C
Shelf Life: at least 12 months
Supplier: CGS

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Price range: $195.70 through $4,560.84

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