The globular subunit of adipocyte complement-related protein of 30 kDa (globular ACRP-30) is a naturally occurring cleavage product of adiponectin. Produced exclusively by adipocytes, globular ACRP-30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. Globular ACRP-30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2).
