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Kinase Compounds

Kinase inhibitors and modulators to a wide range of kinase targets.

AGC Group Kinases: includes AKT, MSK1, p70S6K, PDK1, PKA, PKB, PKC, PKG, PRKX, ROCK, RSK, S6 kinase

Atypical Group Kinases: includes ATM, ATR, BRD, DNA-PK, mTOR

CAMK Group Kinases: includes AMPK, CamKII, CHK, MLCK, Pim

CMGC Group Kinases: includes CDK, ERK, GSK3, JNK, p38 MAPK

Lipid Kinases: includes PI3K

Other Group Kinases: includes AurK, CK, PERK, PLK, TBK, Wee

STE Group Kinases: includes CDPK, HGK, MEK, MKK, MST, PAK, STE

TKL Group Kinases: includes LRRK2 and Raf

Tyrosine Kinase Group: includes ABL, ALK, AXL, BTK, c-Fes, c-Kit, c-Met, CSF-1R, EGFR, EphR, FAK, FGFR, FLT, FYN, HCK, IGF-1R, InsR, JAK, KSR, LCK, PDGFR, RET, RON, ROR, ROS, SRC, SYK, TIE, TRK, VEGFR

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Kinase Categories

AGC Group Kinases

Atypical Group Kinases

CAMK Group Kinases

CMGC Group Kinases

Lipid Kinases

Miscellaneous Protein Kinases

Other Group Kinases

STE Group Kinases

TKL Group Kinases

Tyrosine Kinase Group

 


AGC Group Kinases

4-α-Phorbol-12-myristate-13-acetate (Negative control for PKC activation)

AKRRRLSSLRA (ROCK-2 substrate)

AZD-5363 (AKT inhibitor, potential ROCK, p70S6K, PKA, MKK1, MSK1, MSK2, PKC, PKG, PRKX, RSK2/3 inhibitor)

Benzyl Selenocyanate (potential PKA and PKC inhibitor)

Bryostatin 1 (TLR4 activator, PKC modulator)

BX-795 (PDK1 inhibitor)

Calphostin C (PKC inhibitor)

Chelerythrine Chloride (PKC and Na+/K+ ATPase inhibitor)

CREBtide (PKD1 and PKA substrate)

D-Sphingosine (PKC inhibitor)

Fasudil Hydrochloride (ROCK inhibitor)

GDC-0068 (Akt inhibitor)

Gossypol (calcineurin and PKC inhibitor)

GSK-429286A (ROCK1/2 inhibitor, potential RSK and p70S6K inhibitor)

GSK-690693 (Akt inhibitor)

H7 (PKC and PKG inhibitor)

H8 dihydrochloride (PKA inhibitor)

H89 (PKA inhibitor, potential ROCK, S6K1, MSK1, PKB inhibitor)

Herbimycin A (HSP90, PKC, Src, Bcr-Abl inhibitor)

K252a (PKC inhibitor, TrkA/B antagonist)

K252b (PKC inhibitor)

K252c (PKC and PKA inhibitor)

Katacalcin (PKA activator)

Kemptide (PKA substrate)

KT5720 (PKA and PDK1 inhibitor, HCN channel blocker, potential GSK3, MEK, MSK1, PKB inhibitor)

KT5823 (PKG inhibitor)

L-Selectin (binds PKC, calmodulin)

Malantide (PKA substrate)

MK-2206 (Akt inhibitor)

N,N-dimethyl-Sphingosine (PP2A activator, Sphk1 and PKC inhibitor)

Palmitoyl-D,L-carnitine (PKC inhibitor)

Pantoprazole (H+/K+ ATPase and ROCK-2 inhibitor)

Pantoprazole Sodium Sesquihydrate (H+/K+ ATPase and ROCK-2 inhibitor)

Perifosine (Akt inhibitor)

Phorbol-12,13-dibutyrate (PKC and PKD activator, carcinogen)

Phorbol-12-myristate-13-acetate (PKC activator, carcinogen)

Phosphate Acceptor Peptide (PKC and S6 kinase substrate)

PHT-427 (PDK1 and Akt inhibitor)

PKC412 (PKC and FLT3 inhibitor)

QKRPSQRSKYL (PKC substrate)

Resiniferatoxin (PKC and TRPV agonist)

Resiniferonol-9,13,14-orthophenyl Acetate (potential PKC activator)

RKI-1447 (ROCK1/2 inhibitor)

Staurosporine (PKC and mammalian RNA splicing inhibitor)

Syntide 2 (CDPK, PKC, CaMKII substrate)

Tamoxifen Citrate (FIASMA, SERM, PKC inhibitor)

Thiazovivin (ROCK inhibitor)

Verbascoside (potential PKC, DPP4, prolyl oligopeptidase inhibitor)

VX-11e (ERK2 inhibitor, potential AurKA, GSK3, CDK2, FLT3, ROCK1, JNK3 inhibitor)

Y27632 Dihydrochloride (ROCK inhibitor)

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Atypical Group Kinases

AZD-2014 (mTOR inhibitor)

AZD-8055 (mTOR inhibitor)

BEZ235 (PI3K and mTOR inhibitor)

Bromosporine (BRD2/4/9 and CECR2 inhibitor)

Ciclopirox Olamine (mTOR inhibitor)

CPI-203 (JQ-1 derivative; BRD inhibitor)

Dihydroartemisinin (mTORC1 inhibitor)

Dinaciclib (BRD binding agent, CDK1/2/5/9 inhibitor)

Everolimus (mTORC1 inhibitor)

GDC-0349 (mTOR inhibitor)

GDC-0980 (PI3K and mTOR inhibitor)

GSK-2126458 (p110α PI3K and mTOR inhibitor)

I-BET151 (BRD2/3/4 inhibitor)

INK128 (mTOR inhibitor)

(+)-JQ-1 (BRD inhibitor)

Nordihydroguaiaretic Acid (5-lipoxygenase, AChR, BChE, mTORC1 inhibitor)

NVP-BGT226 (PI3K and mTOR inhibitor)

OSI-027 (mTOR inhibitor)

OTX-015 (BRD2/3/4 inhibitor)

Palomid 529 (mTOR inhibitor)

PF-04691502 Dihydrate (PI3K and mTOR inhibitor)

PFI-1 (BRD2/4 inhibitor)

PKI-402 (p110α PI3K and mTOR inhibitor)

PP-121 (p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR2, PDGFR inhibitor)

PP-242 (mTOR inhibitor)

Rapamycin (mTOR inhibitor)

VE-821 (ATR inhibitor)

Wortmannin (PI3K, mTOR, DNA-PK, PI4K, MLCK, MAPK, PLK inhibitor)

XL-765 (PI3K and mTOR inhibitor)

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CAMK Group Kinases

A-769662 (AMPK activator)

Autocamtide 2 (CamKII substrate)

AZD-1208 (Pim-1 inhibitor)

AZD-7762 Hydrochloride (CHK1 inhibitor)

Bisdemethoxycurcumin (DNMT1 and α-amylase inhibitor, WIF-1 promoter demethylation inhibitor, potential SIRT1 and AMPK activator)

Demethoxycurcumin (AMPK activator, STAT3 and eIF4E-bp3 inhibitor, potential AChE and EGFR inhibitor)

Dimebon Dihydrochloride (AMPK activator, L-type Ca2+ channel and NMDA, histamine H1/2, α-adrenergic, 5-HT2C/5A/6 receptor antagonist)

Ginsenoside Rc (AMPK inhibitor, potential TRPV1 antagonist)

Metformin Hydrochloride (AMPK activator)

Mitoxantrone Dihydrochloride (Pim-1 inhibitor)

Nobiletin (potential AMPA positive modulator)

Olanzapine (AMPK activator, D1-4, 5-HT1A/2/3/6/7, M1-5 mAChR, α1/2-adrenergic antagonist)

PJ34 Hydrochloride (PARP inhibitor; potential Pim1 inhibitor)

Sanguinarine (potential AMPK activator, potential amino acid carboxylase inhibitor)

SCH-900776 (CHK1 inhibitor)

Syntide 2 (CDPK, PKC, CaMKII substrate)

Wortmannin (PI3K, mTOR, DNA-PK, PI4K, MLCK, MAPK, PLK inhibitor)

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CMGC Group Kinases

1-Isothiocyanato-6-(methylsulfinyl)-hexane (GSK-3β inhibitor)

Alsterpaullone (GSK-3 and CDK inhibitor)

ARRY-162 (MEK1/2 and ERK inhibitor)

Cafestol (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Acetate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Eicosanate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Linoleate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Oleate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Palmitate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Stearate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

CV-65 (JNK and ERK5 inhibitor)

CV-66 (JNK and ERK5 inhibitor)

CV-70 (JNK and ERK5 inhibitor)

Dinaciclib (BRD binding agent, CDK1/2/5/9 inhibitor)

Donepezil Hydrochloride (GSK3 and AChE inhibitor, potential σ1 agonist)

Doramapimod (JNK, ALK, p38 MAPK inhibitor)

Famotidine (Histamine H2 antagonist, GSK-3β inhibitor)

Ginkgolide A (GSK-3β inhibitor, potential PXR agonist)

Indirubin (potential EGFR and CDK inhibitor)

Kenpaullone (GSK-3β, HGK, and CDK inhibitor)

KT5720 (PKA and PDK1 inhibitor, HCN channel blocker, potential GSK3, MEK, MSK1, PKB inhibitor)

Luteinizing Hormone Releasing Hormone III, lamprey (GnRH agonist, weak ERK1/2 and p38 MAPK activator)

LY-2090314 (GSK-3 inhibitor)

Manzamine A (vacuolar ATPase uncoupler, GSK3 inhibitor)

[D-Asp3, (E)-Dhb7]-Microcystin-HphR (potential PP1/2A inhibitor, potential GSK-3β activator)

[D-Asp3, (E)-Dhb7]-Microcystin-HtyR (potential PP1/2A inhibitor, potential GSK-3β activator)

[D-Asp3]-Microcystin-LR (PP1/2A inhibitor, potential GSK-3β activator)

Microcystin (N-Me)-LR (PP1/2A inhibitor, potential GSK-3β activator)

Microcystin-LR (PP1/2A inhibitor, potential GSK-3β activator)

[D-Asp3, (E)-Dhb7]-Microcystin-RR (PP1/2A inhibitor, potential GSK-3β activator)

Microcystin-RR (PP1/2A inhibitor, potential GSK-3β activator)

Olomoucine (CDK inhibitor)

Palbociclib Hydrochloride (CDK4/6 inhibitor)

Palbociclib Isethionate (CDK4/6 inhibitor)

Purvalanol A (CDK inhibitor)

Roscovitine (CDK inhibitor, L-type Ca2+ channel blocker)

SB-203580 (p38 MAPK inhibitor)

TDZD-8 (GSK-3β inhibitor)

Tivantinib (MET and GSK-3α/β inhibitor)

VX-11e (ERK2 inhibitor, potential AurKA, GSK3, CDK2, FLT3, ROCK1, JNK3 inhibitor)

VX-702 (p38 MAPK inhibitor)

WHI-P131 (JAK3 and EGFR inhibitor)

Wogonin (CDK9 inhibitor)

Wortmannin (PI3K, mTOR, DNA-PK, PI4K, MLCK, MAPK, PLK inhibitor)

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Lipid Kinases

A66 (p110α PI3K inhibitor)

AS-252424 (p110γ PI3K inhibitor, potential TRPC1/5/6 negative modulator, potential TRPC3/7 positive modulator)

AS-604850 (p110γ PI3K inhibitor)

AS-605240 (p110δ PI3K inhibitor)

AZD-6482 (p110β PI3K inhibitor)

BAY80-6946 (p110α PI3K inhibitor)

BEZ235 (PI3K and mTOR inhibitor)

BKM120 (PI3K inhibitor, microtubule polymerization inhibitor)

BYL719 (p110α PI3K inhibitor)

CAL101 (p110δ PI3K inhibitor)

CAY10505 (p110γ PI3K inhibitor)

CH5132799 (p110α PI3K inhibitor)

CUDC-907 (PI3K and HDAC inhibitor)

GDC-0980 (PI3K and mTOR inhibitor)

GSK-2126458 (p110α PI3K and mTOR inhibitor)

GSK-2334470 (PI3K and PDK1 inhibitor)

GSK-2636771 (p110β PI3K inhibitor)

IC-87114 (p110δ PI3K inhibitor)

IPI-145 (p110δ PI3K inhibitor)

LY-294002 (PI3K inhibitor)

NVP-BGT226 (PI3K and mTOR inhibitor)

PF-04691502 Dihydrate (PI3K and mTOR inhibitor)

Piceatannol (HPH-2 inhibitor, potential PI3K and JAK1 inhibitor)

PIK-293 (p110δ PI3K inhibitor)

PIK-294 (p110δ PI3K inhibitor)

PIK-75 Hydrochloride (p110α PI3K inhibitor)

PIK-93 (p110α and p110γ PI3K inhibitor)

PKI-402 (p110α PI3K and mTOR inhibitor)

PP-121 (p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR2, PDGFR inhibitor)

PX-866 (PI3K inhibitor)

TG100-115 (p110δ and p110γ PI3K inhibitor)

VS-5584 (PI3K inhibitor)

Wortmannin (PI3K, mTOR, DNA-PK, PI4K, MLCK, MAPK, PLK inhibitor)

XL-765 (PI3K and mTOR inhibitor)

YM-201636 (PIKfyve inhibitor)

ZSTK474 (PI3K inhibitor)

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Miscellaneous Protein Kinases

Lonidamine (Hexokinase inhibitor, aerobic glycolysis inhibitor)

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Other Group Kinases

Amlexanox (S100A12 and S100A13 inhibitor, TBK1 inhibitor)

AZD-1152-HQPA (AurKA/B inhibitor)

BI-2536 (PLK1 inhibitor)

BI-6727 (PLK1 inhibitor)

Casein Kinase 2 Assay Kit (Casein kinase 2 substrate)

C-Myc Peptide (PAC1 agonist, CK2 activator)

CYC-116 (AurKB/C inhibitor)

GSK-1070916 (AurKB/C inhibitor)

GSK-2606414 (PERK inhibitor)

GSK-461364 (PLK1 inhibitor)

MK-1775 (Wee1 inhibitor)

MLN8237 (AurKA inhibitor)

NMS-1286937 (PLK1 inhibitor)

Tozasertib (AurK, FLT3, Abl inhibitor)

VX-11e (ERK2 inhibitor, potential AurKA, GSK3, CDK2, FLT3, ROCK1, JNK3 inhibitor)

Wortmannin (PI3K, mTOR, DNA-PK, PI4K, MLCK, MAPK, PLK inhibitor)

ZM-447439 Trihydrate (AurKA/B inhibitor)

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STE Group Kinases

ARRY-162 (MEK1/2 and ERK inhibitor)

AS-703026 (MEK1/2 inhibitor)

AZD-5363 (AKT inhibitor, potential ROCK, p70S6K, PKA, MKK1, MSK1, MSK2, PKC, PKG, PRKX, RSK2/3 inhibitor)

AZD-8330 (MEK 1/2 inhibitor)

Cafestol (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Acetate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Eicosanate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Linoleate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Oleate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Palmitate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Cafestol Stearate (FXR and PXR agonist, ERK2 and MEK1 inhibitor)

Curcumin, high purity (MST1 activator, CRMP2 inhibitor)

GDC-0623 (MEK inhibitor)

GSK-1120212 (MEK1/2 inhibitor)

Kenpaullone (GSK-3β, HGK, and CDK inhibitor)

KT5720 (PKA and PDK1 inhibitor, HCN channel blocker, potential GSK3, MEK, MSK1, PKB inhibitor)

PD-184352 (MEK1/2 and Raf inhibitor)

PD-325901 (MEK1/2 and Raf inhibitor)

PF-03758309 Dihydrochloride (PAK4 inhibitor)

RAF265 (B-Raf, VEGFR2, c-Raf, PDGFR, CSF-1R, RET, c-Kit, Src, STE20 inhibitor)

RDEA119 (MEK1/2 inhibitor)

Selumetinib (MEK1/2 inhibitor)

Syntide 2 (CDPK, PKC, CaMKII substrate)

Trifluoperazine Dihydrochloride (D1/2 and α1-adrenergic antagonist, calmodulin and CDPK4 inhibitor, Nav1.4 and Nav1.7 Na+ channel blocker)

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TKL Group Kinases

AZ-628 (B-Raf and c-Raf inhibitor)

CEP-32496 (V600E B-Raf inhibitor)

Dabrafenib (B-Raf and c-Raf inhibitor)

Dabrafenib Mesylate (B-Raf and c-Raf inhibitor)

GDC-0879 (V600E B-Raf inhibitor)

GNE-7915 (LRRK2 inhibitor)

GW-5074 (c-Raf inhibitor)

MLN2480 (Raf inhibitor)

NVP-TAE684 (ALK, c-Fes, LRRK2 inhibitor)

PD-184352 (MEK1/2 and Raf inhibitor)

PD-325901 (MEK1/2 and Raf inhibitor)

PLX4720 (V600E B-Raf inhibitor)

RAF265 (B-Raf, VEGFR2, c-Raf, PDGFR, CSF-1R, RET, c-Kit, Src, STE20 inhibitor)

SB-590885 (B-Raf inhibitor)

Vemurafenib (B-Raf inhibitor)

ZM-336372 (c-Raf activator, tyrosine kinase inhibitor)

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Tyrosine Kinase Group

4,4′-(1,1′-Biphenyl-4,4′-diyldioxy)dianiline (Potential VEGFR2, Met, RET, Axl, Ron, PDGFR, FGFR1, FLT1/3/4 inhibitor)

7,8-Dihydroxyflavone Hydrate (TrkB agonist)

Afatinib (EGFR inhibitor)

AG-1024 (IGF-1R inhibitor)

AMG-208 (c-MET and Ron inhibitor)

AMG-458 (c-MET inhibitor)

Amitriptyline Hydrochloride (FIASMA, σ1, RyR2, TrkA/B agonist, 5-HT2/6/7, M1-5 mAChR, histamine H1/4, α1-adr. antagonist, SERT, NET inhibitor, Kv1.1/7.2/7.3 K+, L-type Ca2+ channel blocker)

Arenobufagin (VEGFR2 inhibitor, cardiovascular Na+/K+ ATPase inhibitor)

ASP3026 (ALK inhibitor)

AVL-292 (BTK inhibitor)

AZD-1480 (JAK1/2 inhibitor)

AZD-3463 (ALK and IGF-1R inhibitor)

AZD-4547 (FGFR inhibitor)

BMS-599626 (EGFR, VEGFR inhibitor)

BMS-754807 (InsR and IGF-1R inhibitor)

BMS-777607 (MET and Ron inhibitor)

BMS-911543 (JAK2 inhibitor)

Bosutinib, structural isomer (Src and Abl inhibitor)

Cabozantinib (VEGFR2, c-Met, RET inhibitor)

Canertinib Dihydrochloride (EGFR inhibitor)

Cediranib (VEGFR inhibitor)

CH5424802 (ALK inhibitor)

CO-1686 (EGFR (WT, T790M) inhibitor)

Crenolanib (FLT3, PDGFR inhibitor)

Crizotinib (ALK, ROS1, c-MET inhibitor)

CYT-387 (JAK2 inhibitor)

Dacomitinib Monohydrate (EGFR inhibitor)

Dasatinib Monohydrate (Abl, PDGFR, EphR, Src, c-Kit, FYN, LCK, HCK inhibitor)

Defactinib (FAK inhibitor)

Demethoxycurcumin (AMPK activator, STAT3 and eIF4E-bp3 inhibitor, potential AChE and EGFR inhibitor)

Doramapimod (JNK, ALK, p38 MAPK inhibitor)

Erlotinib Hydrochloride (EGFR inhibitor)

Foretinib (ROS1, MET, Ron, Axl, TIE-2, VEGFR2 inhibitor)

Gefitinib (EGFR inhibitor)

GLPG-0634 (JAK1 inhibitor)

GNF-2 (Abl inhibitor)

GS-9973 (Syk inhibitor)

GSK-1838705A (ALK and IGF-1R inhibitor)

GSK-1904529A (InsR and IGF-1R inhibitor)

Herbimycin A (HSP90, PKC, Src, Bcr-Abl inhibitor)

Imatinib Mesylate (Abl, c-Kit, PDGFR inhibitor)

INCB018424 (JAK1/2 inhibitor)

INCB-28060 (c-MET inhibitor)

Indirubin (potential EGFR and CDK inhibitor)

K252a (PKC inhibitor, TrkA/B antagonist)

Lapatinib Ditosylate Monohydrate (EGFR inhibitor)

Lavendustin A (Tyrosine kinase inhibitor)

LDK378 (ALK and IGF-1R inhibitor)

Luteolin (DAT and NET potentiator, HSP90, IGF-1R, PDE inhibitor, potential α2-adrenergic antagonist)

LY-2874455 (FGFR inhibitor)

Masitinib (PDGFR and c-Kit inhibitor)

MK-2461 (MET, FGFR, PDGFR inhibitor)

Motesanib (VEGFR1/2/3, PDGFR, c-Kit, RET inhibitor)

Motesanib Diphosphate (VEGFR, PDGFR, c-Kit, RET inhibitor)

Mubritinib, Free Base (EGFR2 inhibitor)

Neratinib (EGFR inhibitor)

Nilotinib (Abl, c-Kit, PDGFR, PP2A inhibitor)

NVP-BGJ398 (FGFR inhibitor)

NVP-BHG712 (EphB4 inhibitor)

NVP-TAE684 (ALK, c-Fes, LRRK2 inhibitor)

OSI-906 (IGF-1R and InsR inhibitor)

P1 Peptide (prevents EGFR-PLCγ association)

Pazopanib (VEGFR, PDGFR, c-Kit inhibitor)

PCI-32765 (BTK and IL-2-inducible kinase inhibitor)

Pelitinib (EGFR inhibitor)

PF-04217903 (c-MET inhibitor)

Piceatannol (HPH-2 inhibitor, potential PI3K and JAK1 inhibitor)

PKC412 (PKC and FLT3 inhibitor)

PP-1 (Src inhibitor)

PP-121 (p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR2, PDGFR inhibitor)

Quizartinib (FLT3, c-Kit, PDGFR inhibitor)

Radicicol (topoisomerase VI-B, HSP90, Raf, Src family kinase inhibitor)

RAF265 (B-Raf, VEGFR2, c-Raf, PDGFR, CSF-1R, RET, c-Kit, Src, STE20 inhibitor)

Regorafenib Monohydrate (VEGFR1/2/3, TIE2, PDGFRβ, FGFR1, c-Kit, RET, B-Raf inhibitor)

RN-486 (Btk inhibitor)

Rosmarinic Acid (GABA transaminase and Fyn kinase inhibitor)

RR-SRC (Src-derived tyrosine kinase substrate)

Saracatinib (Src and Abl inhibitor)

SB-431542 (ALK4/5/7 (activin-like) inhibitor, TGF-β inhibitor)

SGX-523 (MET inhibitor)

SR1001 (RORα/γ inverse agonist)

SU-1498 (VEGFR inhibitor)

Tandutinib (FLT3, PDGFR, c-Kit inhibitor)

Terbinafine Hydrochloride (squalene oxidase and KSR1 inhibitor)

TG101348 (JAK2 inhibitor)

Tivantinib (MET and GSK-3α/β inhibitor)

Tivozanib (VEGFR1/2/3, c-Kit, PDGFR inhibitor)

Tofacitinib Citrate (JAK1/2/3 inhibitor)

Tozasertib (AurK, FLT3, Abl inhibitor)

Tranilast (TRPV2 antagonist, PDGFR inhibitor)

Triflumizole (PPARγ agonist, RORγ inverse agonist, 14-α demethylase and aromatase inhibitor, ubiquitin/proteasome modulator)

Tyrphostin A25 (SK K+ channel blocker, EGFR inhibitor)

Tyrphostin AG1295 (PDGFR inhibitor)

Tyrphostin AG490 (JAK2 inhibitor, potential EGFR inhibitor)

Vandetanib (RET, EGFR, VEGFR2 inhibitor)

Vatalanib Dihydrochloride (VEGFR inhibitor)

WHI-P131 (JAK3 and EGFR inhibitor)

WZ-4002 (EGFR (T790M) inhibitor)

XL-228 (Abl (T315I) inhibitor)

ZM-336372 (c-Raf activator, tyrosine kinase inhibitor)

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