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Hydrogels

PGD Hydrogels are a family of animal-free, biocompatible and biodegradable synthetic extracellular matrices for cell-based experiments, in vivo cargo delivery and tissue engineering. PGD hydrogel scaffolds are composed of peptides which self-assemble spontaneously to generate a 3D matrix. The hydrogel’s mechanical and chemical properties can be customized according to the needs of the cells or the experimental design and allow easy cell extraction, downstream mRNA and qPCR analysis and cell counting.
 
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PGD hydrogels are suitable for a wide range of applications including 2D and 3D cell cultures, stem cells experiments, in vitro organ models, regenerative medicine, bacteria and virus culturing, vaccine development and drug and biological delivery.
 
Key Features:
  • Ready to use
  • Animal-free, biocompatible and biodegradable
  • Optically transparent
  • Neutral pH under cell culture conditions
  • Offered in a range of electrical net charges and mechanical properties
  • Liquefy under shear and recover instantaneously
  • Easy to handle and transfer to different supports
  • Batch to batch consistency
  • Does not interfere with cell staining
  • Can be customized with functional groups
  • Can be loaded with functional biomolecules or compounds
  • Injectable, sprayable and are naturally mucoadhesive
 
Cell Types Tested:
  • Fibroblasts
  • Human Embryonic Stem Cells
  • Human Induced Pluripotent Stem Cells
  • Human Mesenchymal Stem Cells
  • Bone Marrow Derived Mesenchymal Stem Cells
  • Adipose Tissue Derived Mesenchymal Stem Cells
  • Human Hematopoietic Stem Cells
  • Human Neuronal Stem Cells
  • Cardiac Progenitor Cells
  • Human Endothelial Cells
  • Primary Neurons
  • Cardiomyocytes
  • Nucleus Pulposus Cells
  • Hepatocytes
  • Chondrocytes
  • Myocytes
  • Osteoblasts

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Images Top: Primary rat esophageal stromal fibroblasts cultured in PGD-AlphaPro B. Live cells (green) and dead cells (red). Middle: hMSCs cultured within PGD-Alpha2 using standard osteogenic medium. Bottom: Neuronal Stem Cells differentiation into Neuron Cells in PGD-AlphaPro A.
 
Getting Started with PGD-Hydrogels
Most cells grow well in any of the PGD-Hydrogel formulations. Optimal results will be dependent on cell source, lineage and application in response to gel net charge and firmness. For best performance, it is recommended to optimize conditions using the PGD-Hydrogel Starter Pack which includes 1ml samples of all five formulations.

Featured products within Hydrogels